![]() Our another research theme is to develop novel photonic nanoplatforms for biomedical applications. The powerful spectroscopic techniques enable us to monitor, in real time and in whole time range, the excited state dynamics of noble metals, quantum dots and discrete emissive centers, where the effect can be recovered of surface properties and quantum confinement of electron and/or hole to the photo-excitation and de-excitation dynamics (Nature Nanotechnology 2010). ![]() Our lab is facilitated with femtosecond fluorescence upconversion setup, picosecond time-correlated single-photon-counting setup, confocal microscope and other time-resolved and steady-state spectroscopic facilities. The physical and chemical properties of the emitting elements at initial stage upon external stimuli, play a central role in our research. One of our research themes is the intra- and intermolecular interactions and their interplay in condensed phases under different conditions, for example size confinement, extremely high viscosity, biological surroundings, among which processes like charge generation/recombination, electron transfer, proton transfer, isomerization and conformational changes, solvent reorganization, vibrationalrelaxation (vibrational cooling), often occur (see left figure, Chem. The study is motivated by the scientific challenge it poses to physics and chemistry when the size of a system approaches nanometer scale. The objective of our research is to investigate and design functional molecules and nanostructures with special optical properties which might lead to applications in, among others, biomedical field. Specially confined systems, including nanosystems, are at the forefront of functional material science. Innovation program of State Key Laboratory of Luminescence and Applications, China.Joint PhD training program between The Royal Netherlands Academy of Arts and Sciences (KNAW) and the University of Chinese Academy of Sciences.Joint research program between The Royal Netherlands Academy of Arts and Sciences (KNAW) and Chinese Academy of Sciences (CAS).The Ministry of Economic Affairs of the Netherlands / Agentschap.Netherlands Organisation for Scientific Research.Photonic nanomaterial application for multiple targeting immunoassay.Surface properties of bio-functional nanoparticles.Excitation energy migration dynamics in bio-functional nanomaterials.Ultrafast spectroscopic study of photonic nanomaterials.Bio-nanoplatform constructed by luminescence upconversion nanocrystals.Image-guided and/or targeted cancer therapy ( e.g.photodynamic therapy/immunotherapy/chemotherapy/radiotherapy) based on photonic nanoparticles. ![]()
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